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Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice

Spondweni virus (SPOV) is the flavivirus that is most closely related to Zika virus (ZIKV). Although SPOV causes sporadic human infections in Africa, recently it was found in Culex mosquitoes in Haiti. To investigate the pathogenic spectrum of SPOV, we developed infection models in mice. Although tw...

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Detalles Bibliográficos
Autores principales: Salazar, Vanessa, Jagger, Brett W., Mongkolsapaya, Juthathip, Burgomaster, Katherine E., Dejnirattisai, Wanwisa, Winkler, Emma S., Fernandez, Estefania, Nelson, Christopher A., Fremont, Daved H., Pierson, Theodore C., Crowe, James E., Screaton, Gavin R., Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420780/
https://www.ncbi.nlm.nih.gov/pubmed/30726740
http://dx.doi.org/10.1016/j.celrep.2019.01.052