Phase 1B Study of Momelotinib Combined With Trametinib in Metastatic, Kirsten Rat Sarcoma Viral Oncogene Homolog-Mutated None—Small-Cell Lung Cancer After Platinum-Based Chemotherapy Treatment Failure

We evaluated the multitargeted Janus kinase/TRAF family member associated NF-κβ activator (TANK)-binding kinase 1 (TBK1) inhibitor momelotinib combined with trametinib in 21 patients with Kirsten rat sarcoma viral oncogene homolog-mutated non—small-cell lung cancer. The maximum tolerated dose of mom...

Descripción completa

Detalles Bibliográficos
Autores principales: Barbie, David A., Spira, Alexander, Kelly, Karen, Humeniuk, Rita, Kawashima, Jun, Kong, Shengchun, Koczywas, Marianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420784/
https://www.ncbi.nlm.nih.gov/pubmed/30087028
http://dx.doi.org/10.1016/j.cllc.2018.07.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420784/
https://www.ncbi.nlm.nih.gov/pubmed/30087028
http://dx.doi.org/10.1016/j.cllc.2018.07.004

Ejemplares similares