Utilizing cell line-derived organoids to evaluate the efficacy of a novel LIFR-inhibitor, EC359 in targeting pancreatic tumor stroma

Survival of pancreatic cancer (PC) patient is poor due to lack of effective treatment modalities, which is partly due to the presence of dense desmoplasia that impedes the delivery of chemotherapeutics. Therefore, PC stroma-targeting therapies are expected to improve the efficacy of chemotherapeutic...

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Detalles Bibliográficos
Autores principales: Hall, Bradley R., Cannon, Andrew, Thompson, Christopher, Santhamma, Bindu, Chavez-Riveros, Alejandra, Bhatia, Rakesh, Nair, Hareesh B., Nickisch, Klaus, Batra, Surinder K., Kumar, Sushil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420790/
https://www.ncbi.nlm.nih.gov/pubmed/30899415
http://dx.doi.org/10.18632/genesandcancer.184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420790/
https://www.ncbi.nlm.nih.gov/pubmed/30899415
http://dx.doi.org/10.18632/genesandcancer.184

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