Mechanisms protecting host cells against bacterial pore-forming toxins

Pore-forming toxins (PFTs) are key virulence determinants produced and secreted by a variety of human bacterial pathogens. They disrupt the plasma membrane (PM) by generating stable protein pores, which allow uncontrolled exchanges between the extracellular and intracellular milieus, dramatically di...

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Detalles Bibliográficos
Autores principales: Brito, Cláudia, Cabanes, Didier, Sarmento Mesquita, Francisco, Sousa, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420883/
https://www.ncbi.nlm.nih.gov/pubmed/30591958
http://dx.doi.org/10.1007/s00018-018-2992-8