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Gene overexpression screen for chromosome instability in yeast primarily identifies cell cycle progression genes
Loss of heterozygosity (LOH) in a vegetatively growing diploid cell signals irregularity of mitosis. Therefore, assays of LOH serve to discover pathways critical for proper replication and segregation of chromosomes. We screened for enhanced LOH in a whole-genome collection of diploid yeast strains...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420891/ https://www.ncbi.nlm.nih.gov/pubmed/30244280 http://dx.doi.org/10.1007/s00294-018-0885-x |