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Gene overexpression screen for chromosome instability in yeast primarily identifies cell cycle progression genes

Loss of heterozygosity (LOH) in a vegetatively growing diploid cell signals irregularity of mitosis. Therefore, assays of LOH serve to discover pathways critical for proper replication and segregation of chromosomes. We screened for enhanced LOH in a whole-genome collection of diploid yeast strains...

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Detalles Bibliográficos
Autores principales: Tutaj, Hanna, Pogoda, Elzbieta, Tomala, Katarzyna, Korona, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420891/
https://www.ncbi.nlm.nih.gov/pubmed/30244280
http://dx.doi.org/10.1007/s00294-018-0885-x