A Bivalent Recombinant Mycobacterium bovis BCG Expressing the S1 Subunit of the Pertussis Toxin Induces a Polyfunctional CD4(+) T Cell Immune Response

BACKGROUND: A recombinant BCG strain expressing the genetically detoxified S1 subunit of pertussis toxin 9K/129G (rBCG-S1PT), previously constructed by our research group, demonstrated the ability to develop high protection in mouse models of pertussis challenge which correlated with the induction o...

Descripción completa

Detalles Bibliográficos
Autores principales: Kanno, Alex I., Goulart, Cibelly, Leite, Luciana C. C., Pagliarone, Ana C., Nascimento, Ivan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420988/
https://www.ncbi.nlm.nih.gov/pubmed/30941374
http://dx.doi.org/10.1155/2019/9630793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420988/
https://www.ncbi.nlm.nih.gov/pubmed/30941374
http://dx.doi.org/10.1155/2019/9630793

Ejemplares similares