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MicroRNA-596 acts as a tumor suppressor in gastric cancer and is upregulated by promotor demethylation

BACKGROUND: In the present study, we investigated a suppressive role of microRNA-596 (miR-596) in gastric cancer (GC). Moreover, the downregulation of miR-596 in GC cell lines was associated with an increase of miR-596 promoter methylation. We also established that miR-596 controls the expression of...

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Detalles Bibliográficos
Autores principales: Zhang, Zhen, Dai, Dong-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421237/
https://www.ncbi.nlm.nih.gov/pubmed/30886505
http://dx.doi.org/10.3748/wjg.v25.i10.1224