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Influence of Normal Aging on Brain Autophagy: A Complex Scenario
Misfolded proteins are pathological findings in some chronic neurodegenerative disorders including Alzheimer’s, Parkinson’s, and Huntington’s diseases. Aging is a major risk factor for these disorders, suggesting that the mechanisms responsible for clearing misfolded proteins from the brain, the ubi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421305/ https://www.ncbi.nlm.nih.gov/pubmed/30914945 http://dx.doi.org/10.3389/fnagi.2019.00049 |