Curcumin regulates the miR-21/PTEN/Akt pathway and acts in synergy with PD98059 to induce apoptosis of human gastric cancer MGC-803 cells

OBJECTIVE: PD98059 is a potent and selective inhibitor of mitogen-activated protein kinase. Substantial preclinical evidence has shown an anti-tumor effect of curcumin on various solid tumors. This study aimed to investigate whether curcumin synergistically acts with PD98059 in exerting anti-gastric...

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Detalles Bibliográficos
Autores principales: Qiang, Zhanrong, Meng, Lingyu, Yi, Caixia, Yu, Lianying, Chen, Wenxia, Sha, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Pre-Clinical Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421392/
https://www.ncbi.nlm.nih.gov/pubmed/30727807
http://dx.doi.org/10.1177/0300060518822213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421392/
https://www.ncbi.nlm.nih.gov/pubmed/30727807
http://dx.doi.org/10.1177/0300060518822213

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