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Curcumin regulates the miR-21/PTEN/Akt pathway and acts in synergy with PD98059 to induce apoptosis of human gastric cancer MGC-803 cells
OBJECTIVE: PD98059 is a potent and selective inhibitor of mitogen-activated protein kinase. Substantial preclinical evidence has shown an anti-tumor effect of curcumin on various solid tumors. This study aimed to investigate whether curcumin synergistically acts with PD98059 in exerting anti-gastric...
Autores principales: | Qiang, Zhanrong, Meng, Lingyu, Yi, Caixia, Yu, Lianying, Chen, Wenxia, Sha, Weihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421392/ https://www.ncbi.nlm.nih.gov/pubmed/30727807 http://dx.doi.org/10.1177/0300060518822213 |
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