Complex modifier landscape underlying genetic background effects

The phenotypic consequence of a given mutation can be influenced by the genetic background. For example, conditional gene essentiality occurs when the loss of function of a gene causes lethality in one genetic background but not another. Between two individual Saccharomyces cerevisiae strains, S288c...

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Detalles Bibliográficos
Autores principales: Hou, Jing, Tan, Guihong, Fink, Gerald R., Andrews, Brenda J., Boone, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421401/
https://www.ncbi.nlm.nih.gov/pubmed/30804202
http://dx.doi.org/10.1073/pnas.1820915116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421401/
https://www.ncbi.nlm.nih.gov/pubmed/30804202
http://dx.doi.org/10.1073/pnas.1820915116

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