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Atorvastatin (Lipitor) by MCR
[Image: see text] A concise and convergent synthesis of the atorvastatin, the best-selling cardiovascular drug of all time, is presented. Our approach is based on an Ugi reaction, which shortens the current synthetic route and is advantageous over the published syntheses.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421582/ https://www.ncbi.nlm.nih.gov/pubmed/30891146 http://dx.doi.org/10.1021/acsmedchemlett.8b00579 |