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A comprehensive characterisation of large-scale expanded human bone marrow and umbilical cord mesenchymal stem cells

BACKGROUND: The manufacture of mesenchymal stem/stromal cells (MSCs) for clinical use needs to be cost effective, safe and scaled up. Current methods of expansion on tissue culture plastic are labour-intensive and involve several ‘open’ procedures. We have used the closed Quantum® hollow fibre biore...

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Detalles Bibliográficos
Autores principales: Mennan, Claire, Garcia, John, Roberts, Sally, Hulme, Charlotte, Wright, Karina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421680/
https://www.ncbi.nlm.nih.gov/pubmed/30885254
http://dx.doi.org/10.1186/s13287-019-1202-4