MCT-1/miR-34a/IL-6/IL-6R signaling axis promotes EMT progression, cancer stemness and M2 macrophage polarization in triple-negative breast cancer

BACKGROUND: Triple-negative breast cancer (TNBC) is a poor prognostic breast cancer with the highest mutations and limited therapeutic choices. Cytokine networking between cancer cells and the tumor microenvironment (TME) maintains the self-renewing subpopulation of breast cancer stem cells (BCSCs)...

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Detalles Bibliográficos
Autores principales: Weng, Yueh-Shan, Tseng, Hong-Yu, Chen, Yen-An, Shen, Pei-Chun, Al Haq, Aushia Tanzih, Chen, Li-Mei, Tung, Yi-Chung, Hsu, Hsin-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421700/
https://www.ncbi.nlm.nih.gov/pubmed/30885232
http://dx.doi.org/10.1186/s12943-019-0988-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421700/
https://www.ncbi.nlm.nih.gov/pubmed/30885232
http://dx.doi.org/10.1186/s12943-019-0988-0

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