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A selective c-Met and Trks inhibitor Indo5 suppresses hepatocellular carcinoma growth

BACKGROUND: Human hepatocellular carcinoma (HCC) lacks effective curative therapy and there is an urgent need to develop a novel molecular-targeted therapy for HCC. Selective tyrosine kinase inhibitors have shown promise in treating cancers including HCC. Tyrosine kinases c-Met and Trks are potentia...

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Detalles Bibliográficos
Autores principales: Luo, Teng, Zhang, Shou-Guo, Zhu, Ling-Fei, Zhang, Fei-Xiang, Li, Wei, Zhao, Ke, Wen, Xiao-Xue, Yu, Miao, Zhan, Yi-Qun, Chen, Hui, Ge, Chang-Hui, Gao, Hui-Ying, Wang, Lin, Yang, Xiao-Ming, Li, Chang-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421704/
https://www.ncbi.nlm.nih.gov/pubmed/30885237
http://dx.doi.org/10.1186/s13046-019-1104-4