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Glycine Suppresses AGE/RAGE Signaling Pathway and Subsequent Oxidative Stress by Restoring Glo1 Function in the Aorta of Diabetic Rats and in HUVECs

Oxidative stress plays a crucial role in the pathogenesis of diabetic vascular complications. It is known that the accumulation of advanced glycation end products (AGEs) and the activation of the receptor of AGEs (RAGE) induce sustained oxidative stress in the vascular tissue. Growing evidence indic...

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Detalles Bibliográficos
Autores principales: Wang, Ziwei, Zhang, Junqing, Chen, Lei, Li, Jingjing, Zhang, Hong, Guo, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421782/
https://www.ncbi.nlm.nih.gov/pubmed/30944692
http://dx.doi.org/10.1155/2019/4628962