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The Liver X Receptor Is Upregulated in Monocyte-Derived Macrophages and Modulates Inflammatory Cytokines Based on LXRα Polymorphism

Liver X receptors (LXRs) have emerged as important regulators of inflammatory gene expression. Previously, we had reported that an LXRα gene promoter polymorphism (-1830 T > C) is associated with systemic lupus erythematosus (SLE). Therefore, we assessed cytokine expression in relation to LXRα po...

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Detalles Bibliográficos
Autores principales: Kim, Hyoun-Ah, Baek, Wook-Young, Han, Mi-Hwa, Jung, Ju-Yang, Suh, Chang-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421810/
https://www.ncbi.nlm.nih.gov/pubmed/30944547
http://dx.doi.org/10.1155/2019/6217548