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Accelerated (19)F·MRI Detection of Matrix Metalloproteinase-2/-9 through Responsive Deactivation of Paramagnetic Relaxation Enhancement

Paramagnetic gadolinium ions (Gd(III)), complexed within DOTA-based chelates, have become useful tools to increase the magnetic resonance imaging (MRI) contrast in tissues of interest. Recently, “on/off” probes serving as (19)F·MRI biosensors for target enzymes have emerged that utilize the increase...

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Detalles Bibliográficos
Autores principales: Faas, Henryk M., Krupa, James L., Taylor, Alexander J., Zamberlan, Francesco, Philp, Christopher J., Williams, Huw E. L., Johnson, Simon R., Pavlovskaya, Galina E., Thomas, Neil R., Meersmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421815/
https://www.ncbi.nlm.nih.gov/pubmed/30944549
http://dx.doi.org/10.1155/2019/4826520