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Melatonin Enhances Cisplatin and Radiation Cytotoxicity in Head and Neck Squamous Cell Carcinoma by Stimulating Mitochondrial ROS Generation, Apoptosis, and Autophagy

Head and neck cancer is the sixth leading cancer by incidence worldwide. Unfortunately, drug resistance and relapse are the principal limitations of clinical oncology for many patients, and the failure of conventional treatments is an extremely demoralizing experience. It is therefore crucial to fin...

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Detalles Bibliográficos
Autores principales: Fernandez-Gil, Beatriz I., Guerra-Librero, Ana, Shen, Ying-Qiang, Florido, Javier, Martínez-Ruiz, Laura, García-López, Sergio, Adan, Christian, Rodríguez-Santana, César, Acuña-Castroviejo, Darío, Quiñones-Hinojosa, Alfredo, Fernández-Martínez, José, Abdel Moneim, Ahmed E., López, Luis C., Rodríguez Ferrer, José M., Escames, Germaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421819/
https://www.ncbi.nlm.nih.gov/pubmed/30944696
http://dx.doi.org/10.1155/2019/7187128