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Polyprotein processing and intermolecular interactions within the viral replication complex spatially and temporally control norovirus protease activity

Norovirus infections are a major cause of acute viral gastroenteritis and a significant burden on global human health. A vital process for norovirus replication is the processing of the nonstructural polyprotein by a viral protease into the viral components required to form the viral replication com...

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Detalles Bibliográficos
Autores principales: Emmott, Edward, de Rougemont, Alexis, Hosmillo, Myra, Lu, Jia, Fitzmaurice, Timothy, Haas, Jürgen, Goodfellow, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422069/
https://www.ncbi.nlm.nih.gov/pubmed/30647130
http://dx.doi.org/10.1074/jbc.RA118.006780