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Polyprotein processing and intermolecular interactions within the viral replication complex spatially and temporally control norovirus protease activity
Norovirus infections are a major cause of acute viral gastroenteritis and a significant burden on global human health. A vital process for norovirus replication is the processing of the nonstructural polyprotein by a viral protease into the viral components required to form the viral replication com...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422069/ https://www.ncbi.nlm.nih.gov/pubmed/30647130 http://dx.doi.org/10.1074/jbc.RA118.006780 |