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A nuclear shift of GSK3β protein is an independent prognostic factor in prostate cancer

Glycogen synthase kinase 3ß (GSK3ß) regulates many cancer relevant cellular processes and represents a potential therapeutic target. GSK3ß overexpression has been linked to adverse tumor features in many cancers, but its role in prostate cancer remains uncertain. We employed immunohistochemical GSK3...

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Detalles Bibliográficos
Autores principales: Eichenauer, Till, Hussein, Mohammad, Hube-Magg, Claudia, Kluth, Martina, Büscheck, Franziska, Höflmayer, Doris, Tsourlakis, Maria Christina, Steurer, Stefan, Clauditz, Till S., Luebke, Andreas M., Burandt, Eike, Wilczak, Waldemar, Hinsch, Andrea, Dum, David, Beyer, Burkhard, Steuber, Thomas, Huland, Hartwig, Graefen, Markus, Simon, Ronald, Sauter, Guido, Melling, Nathaniel, Schlomm, Thorsten, Minner, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422199/
https://www.ncbi.nlm.nih.gov/pubmed/30899444
http://dx.doi.org/10.18632/oncotarget.26739