Statins affect human glioblastoma and other cancers through TGF-β inhibition

The cholesterol-lowering statins have known anti-cancer effects, but the mechanisms and how to utilize statins in oncology have been unclear. We noted in the CellMiner database that statin activity against cancer lines correlated with higher expression of TGF-β target genes such as SERPINE1 and ZYX....

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Detalles Bibliográficos
Autores principales: Xiao, Aizhen, Brenneman, Breanna, Floyd, Desiree, Comeau, Laurey, Spurio, Kelsey, Olmez, Inan, Lee, Jeongwu, Nakano, Ichiro, Godlewski, Jakub, Bronisz, Agnieszka, Kagaya, Noritaka, Shin-ya, Kazuo, Purow, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422202/
https://www.ncbi.nlm.nih.gov/pubmed/30899443
http://dx.doi.org/10.18632/oncotarget.26733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422202/
https://www.ncbi.nlm.nih.gov/pubmed/30899443
http://dx.doi.org/10.18632/oncotarget.26733

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