Modeling individual time courses of thrombopoiesis during multi-cyclic chemotherapy

BACKGROUND: Thrombocytopenia is a major side-effect of cytotoxic cancer therapies. The aim of precision medicine is to develop therapy modifications accounting for the individual’s risk. METHODOLOGY/PRINCIPLE FINDINGS: To solve this task, we develop an individualized bio-mechanistic model of the dyn...

Descripción completa

Detalles Bibliográficos
Autores principales: Kheifetz, Yuri, Scholz, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422316/
https://www.ncbi.nlm.nih.gov/pubmed/30840616
http://dx.doi.org/10.1371/journal.pcbi.1006775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422316/
https://www.ncbi.nlm.nih.gov/pubmed/30840616
http://dx.doi.org/10.1371/journal.pcbi.1006775

Ejemplares similares