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Modeling individual time courses of thrombopoiesis during multi-cyclic chemotherapy
BACKGROUND: Thrombocytopenia is a major side-effect of cytotoxic cancer therapies. The aim of precision medicine is to develop therapy modifications accounting for the individual’s risk. METHODOLOGY/PRINCIPLE FINDINGS: To solve this task, we develop an individualized bio-mechanistic model of the dyn...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422316/ https://www.ncbi.nlm.nih.gov/pubmed/30840616 http://dx.doi.org/10.1371/journal.pcbi.1006775 |