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Multiparametric analysis of CD8(+) T cell compartment phenotype in chronic lymphocytic leukemia reveals a signature associated with progression toward therapy

CD8(+) T cells are frontline defenders against cancer and primary targets of current immunotherapies. In CLL, specific functional alterations have been described in circulating CD8(+) T cells, yet a global view of the CD8(+) T cell compartment phenotype and of its real impact on disease progression...

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Detalles Bibliográficos
Autores principales: Gonnord, Pauline, Costa, Manon, Abreu, Arnaud, Peres, Michael, Ysebaert, Loïc, Gadat, Sébastien, Valitutti, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422371/
https://www.ncbi.nlm.nih.gov/pubmed/30906665
http://dx.doi.org/10.1080/2162402X.2019.1570774