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Detection of neoantigen-specific T cells following a personalized vaccine in a patient with glioblastoma
Neoantigens represent promising targets for personalized cancer vaccine strategies. However, the feasibility of this approach in lower mutational burden tumors like glioblastoma (GBM) remains unknown. We have previously reported the use of an immunogenomics pipeline to identify candidate neoantigens...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422384/ https://www.ncbi.nlm.nih.gov/pubmed/30906654 http://dx.doi.org/10.1080/2162402X.2018.1561106 |