Detection of neoantigen-specific T cells following a personalized vaccine in a patient with glioblastoma

Neoantigens represent promising targets for personalized cancer vaccine strategies. However, the feasibility of this approach in lower mutational burden tumors like glioblastoma (GBM) remains unknown. We have previously reported the use of an immunogenomics pipeline to identify candidate neoantigens...

Descripción completa

Detalles Bibliográficos
Autores principales: Johanns, Tanner M., Miller, Christopher A., Liu, Connor J., Perrin, Richard J., Bender, Diane, Kobayashi, Dale K., Campian, Jian L., Chicoine, Michael R., Dacey, Ralph G., Huang, Jiayi, Fritsch, Edward F., Gillanders, William E., Artyomov, Maxim N., Mardis, Elaine R., Schreiber, Robert D., Dunn, Gavin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422384/
https://www.ncbi.nlm.nih.gov/pubmed/30906654
http://dx.doi.org/10.1080/2162402X.2018.1561106

Ejemplares similares

Ejemplares similares