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Prognostic significance of circulating PD-1, PD-L1, pan-BTN3As, BTN3A1 and BTLA in patients with pancreatic adenocarcinoma

PDAC is one of the most heterogeneous cancers with low chemotherapeutic sensitivity due to a dense stroma, a weak vasculature and significant biological aggressivity. In cancer, suppressive immune checkpoints are often hyper-activated to ensure an effective evasion of tumor cells from immune surveil...

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Detalles Bibliográficos
Autores principales: Bian, Benjamin, Fanale, Daniele, Dusetti, Nelson, Roque, Julie, Pastor, Sonia, Chretien, Anne-Sophie, Incorvaia, Lorena, Russo, Antonio, Olive, Daniel, Iovanna, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422385/
https://www.ncbi.nlm.nih.gov/pubmed/30906655
http://dx.doi.org/10.1080/2162402X.2018.1561120