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In vitro generation of tau aggregates conformationally distinct from parent tau seeds of Alzheimer’s brain
Normal monomeric tau can be converted into pathogenic aggregates and acquire protease resistance in a prion-like manner. This acquisition of partial protease-resistance in tau aggregates has to date only been partially investigated in various studies exploring the prion-like properties of tau. In th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422395/ https://www.ncbi.nlm.nih.gov/pubmed/30422056 http://dx.doi.org/10.1080/19336896.2018.1545524 |