Engineering of solidified glyburide nanocrystals for tablet formulation via loading of carriers: downstream processing, characterization, and bioavailability

INTRODUCTION: Presenting poorly water-soluble drugs as nanoparticles has shown to be an effective technique in enhancing drug dissolution rate, intrinsic solubility, and thus oral bioavailability. Nevertheless, working with nanoparticles introduces many challenges, one of which is their physical ins...

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Detalles Bibliográficos
Autores principales: Ali, Hany S M, Hanafy, Ahmed F, Alqurshi, Abdulmalik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422418/
https://www.ncbi.nlm.nih.gov/pubmed/30936692
http://dx.doi.org/10.2147/IJN.S194734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422418/
https://www.ncbi.nlm.nih.gov/pubmed/30936692
http://dx.doi.org/10.2147/IJN.S194734

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