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Discovery of a novel DNA polymerase inhibitor and characterization of its antiproliferative properties
Chromosomal duplication is targeted by various chemotherapeutic agents for the treatment of cancer. However, there is no specific inhibitor of DNA polymerases that is viable for cancer management. Through structure-based in silico screening of the ZINC database, we identified a specific inhibitor of...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422523/ https://www.ncbi.nlm.nih.gov/pubmed/30427259 http://dx.doi.org/10.1080/15384047.2018.1529126 |