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Discovery of a novel DNA polymerase inhibitor and characterization of its antiproliferative properties

Chromosomal duplication is targeted by various chemotherapeutic agents for the treatment of cancer. However, there is no specific inhibitor of DNA polymerases that is viable for cancer management. Through structure-based in silico screening of the ZINC database, we identified a specific inhibitor of...

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Detalles Bibliográficos
Autores principales:	Mishra, Bhanvi, Zhang, Sufang, Zhao, Hong, Darzynkiewicz, Zbigniew, Lee, Ernest Y.C., Lee, Marietta Y.W.T., Zhang, Zhongtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422523/ https://www.ncbi.nlm.nih.gov/pubmed/30427259 http://dx.doi.org/10.1080/15384047.2018.1529126

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