Cargando…

A Novel Multiplex PCR-RFLP Method for Simultaneous Genotyping of CYP3A4*4 A>G, CYP3A4*18B G>A and CYP3A4*22 C>T

BACKGROUND: Cytochrome P450 3A enzymes exhibit a variety of physiological roles and have been reported to be the most predominant enzymes involved in drugs metabolism. Single nucleotide polymorphisms (SNPs) in the genes that code for these enzymes may result in functional changes that affect enzyme...

Descripción completa

Detalles Bibliográficos
Autores principales: Abubakar, Murtala Bello, Tan, Huay Lin, Gan, Siew Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Penerbit Universiti Sains Malaysia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422546/
https://www.ncbi.nlm.nih.gov/pubmed/30914849
http://dx.doi.org/10.21315/mjms2018.25.4.7