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Screening the RFX6-DNA binding domain for potential genetic variants in patients with type 2 diabetes

BACKGROUND: The regulatory factor X6 (RFX6), a member of regulatory factor X family, is known to play a key role in the development and differentiation of pancreatic beta cells as well as insulin production and secretion. However, the potential role of RFX6 in type 2 diabetes (T2D) is still unclear....

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Detalles Bibliográficos
Autores principales: Mahmoud, Ismail Sami, Homsi, Ayat, Al-Ameer, Hamzeh J, Alzyoud, Jihad, Darras, Mais, Shhab, Mohammad Al, Zihlif, Malek, Hatmal, Ma’mon M, Alshaer, Walhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422854/
https://www.ncbi.nlm.nih.gov/pubmed/30891153
http://dx.doi.org/10.4239/wjd.v10.i3.181