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HER2 decreases drug sensitivity of ovarian cancer cells via inducing stem cell-like property in an NFκB-dependent way

Increasing evidence shows that cancer stem cells are responsible for drug resistance and relapse of tumors. In breast cancer, human epidermal growth factor receptor 2 (HER2) induces Herceptin resistance by inducing cancer stem cells. In the present study, we explored the effect of HER2 on cancer ste...

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Detalles Bibliográficos
Autores principales: Wang, Wenxiang, Gao, Yuxia, Hai, Jing, Yang, Jing, Duan, Shufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422889/
https://www.ncbi.nlm.nih.gov/pubmed/30314995
http://dx.doi.org/10.1042/BSR20180829