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Cortical GABAergic Dysfunction in Stress and Depression: New Insights for Therapeutic Interventions

Major depressive disorder (MDD) is a debilitating illness characterized by neuroanatomical and functional alterations in limbic structures, notably the prefrontal cortex (PFC), that can be precipitated by exposure to chronic stress. For decades, the monoaminergic deficit hypothesis of depression pro...

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Detalles Bibliográficos
Autores principales: Fogaça, Manoela V., Duman, Ronald S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422907/
https://www.ncbi.nlm.nih.gov/pubmed/30914923
http://dx.doi.org/10.3389/fncel.2019.00087