Utility of cfDNA Fragmentation Patterns in Designing the Liquid Biopsy Profiling Panels to Improve Their Sensitivity

Genotyping of cell-free DNA (cfDNA) in plasma samples has the potential to allow for a noninvasive assessment of tumor biology, avoiding the inherent shortcomings of tissue biopsy. Next generation sequencing (NGS), a leading technology for liquid biopsy analysis, continues to be hurdled with several...

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Detalles Bibliográficos
Autores principales: Ivanov, Maxim, Chernenko, Polina, Breder, Valery, Laktionov, Konstantin, Rozhavskaya, Ekaterina, Musienko, Sergey, Baranova, Ancha, Mileyko, Vladislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422983/
https://www.ncbi.nlm.nih.gov/pubmed/30915108
http://dx.doi.org/10.3389/fgene.2019.00194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422983/
https://www.ncbi.nlm.nih.gov/pubmed/30915108
http://dx.doi.org/10.3389/fgene.2019.00194

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