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Utility of cfDNA Fragmentation Patterns in Designing the Liquid Biopsy Profiling Panels to Improve Their Sensitivity

Genotyping of cell-free DNA (cfDNA) in plasma samples has the potential to allow for a noninvasive assessment of tumor biology, avoiding the inherent shortcomings of tissue biopsy. Next generation sequencing (NGS), a leading technology for liquid biopsy analysis, continues to be hurdled with several...

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Detalles Bibliográficos
Autores principales:	Ivanov, Maxim, Chernenko, Polina, Breder, Valery, Laktionov, Konstantin, Rozhavskaya, Ekaterina, Musienko, Sergey, Baranova, Ancha, Mileyko, Vladislav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422983/ https://www.ncbi.nlm.nih.gov/pubmed/30915108 http://dx.doi.org/10.3389/fgene.2019.00194

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