Dual-FRET imaging of IP(3) and Ca(2+) revealed Ca(2+)-induced IP(3) production maintains long lasting Ca(2+) oscillations in fertilized mouse eggs

In most species, fertilization induces Ca(2+) transients in the egg. In mammals, the Ca(2+) rises are triggered by phospholipase Cζ (PLCζ) released from the sperm; IP(3) generated by PLCζ induces Ca(2+) release from the intracellular Ca(2+) store through IP(3) receptor, termed IP(3)-induced Ca(2+) r...

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Detalles Bibliográficos
Autores principales: Matsu-ura, Toru, Shirakawa, Hideki, Suzuki, Kenichi G. N., Miyamoto, Akitoshi, Sugiura, Kotomi, Michikawa, Takayuki, Kusumi, Akihiro, Mikoshiba, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423007/
https://www.ncbi.nlm.nih.gov/pubmed/30886280
http://dx.doi.org/10.1038/s41598-019-40931-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423007/
https://www.ncbi.nlm.nih.gov/pubmed/30886280
http://dx.doi.org/10.1038/s41598-019-40931-w

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