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Dual-FRET imaging of IP(3) and Ca(2+) revealed Ca(2+)-induced IP(3) production maintains long lasting Ca(2+) oscillations in fertilized mouse eggs
In most species, fertilization induces Ca(2+) transients in the egg. In mammals, the Ca(2+) rises are triggered by phospholipase Cζ (PLCζ) released from the sperm; IP(3) generated by PLCζ induces Ca(2+) release from the intracellular Ca(2+) store through IP(3) receptor, termed IP(3)-induced Ca(2+) r...
Autores principales: | Matsu-ura, Toru, Shirakawa, Hideki, Suzuki, Kenichi G. N., Miyamoto, Akitoshi, Sugiura, Kotomi, Michikawa, Takayuki, Kusumi, Akihiro, Mikoshiba, Katsuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423007/ https://www.ncbi.nlm.nih.gov/pubmed/30886280 http://dx.doi.org/10.1038/s41598-019-40931-w |
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