Ataxia-Telangiectasia Mutated is located in cardiac mitochondria and impacts oxidative phosphorylation

The absence of Ataxia-Telangiectasia mutated protein kinase (ATM) is associated with neurological, metabolic and cardiovascular defects. The protein has been associated with mitochondria and its absence results in mitochondrial dysfunction. Furthermore, it can be activated in the cytosol by mitochon...

Descripción completa

Detalles Bibliográficos
Autores principales: Blignaut, Marguerite, Loos, Ben, Botchway, Stanley W., Parker, Anthony W., Huisamen, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423017/
https://www.ncbi.nlm.nih.gov/pubmed/30886180
http://dx.doi.org/10.1038/s41598-019-41108-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423017/
https://www.ncbi.nlm.nih.gov/pubmed/30886180
http://dx.doi.org/10.1038/s41598-019-41108-1

Ejemplares similares