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Ataxia-Telangiectasia Mutated is located in cardiac mitochondria and impacts oxidative phosphorylation
The absence of Ataxia-Telangiectasia mutated protein kinase (ATM) is associated with neurological, metabolic and cardiovascular defects. The protein has been associated with mitochondria and its absence results in mitochondrial dysfunction. Furthermore, it can be activated in the cytosol by mitochon...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423017/ https://www.ncbi.nlm.nih.gov/pubmed/30886180 http://dx.doi.org/10.1038/s41598-019-41108-1 |