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Sulfate depletion triggers overproduction of phospholipids and the release of outer membrane vesicles by Neisseria meningitidis

Outer membrane vesicles (OMVs) produced by bacteria are interesting vaccine candidates. OMVs are nanoparticles that contain many immunogenic components, are self-adjuvating, and non-replicative. Despite recent insights in the biogenesis of OMVs, there is no consensus on a conserved mechanism of OMV...

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Detalles Bibliográficos
Autores principales: Gerritzen, Matthias J. H., Martens, Dirk E., Uittenbogaard, Joost P., Wijffels, René H., Stork, Michiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423031/
https://www.ncbi.nlm.nih.gov/pubmed/30886228
http://dx.doi.org/10.1038/s41598-019-41233-x