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Comparative Description of the Expression Profile of Interferon-Stimulated Genes in Multiple Cell Lineages Targeted by HIV-1 Infection

Immediately after viral infections, innate immune sensors recognize viruses and lead to the production of type I interferon (IFN-I). IFN-I upregulates various genes, referred to as IFN-stimulated genes (ISGs), and some ISGs inhibit viral replication. HIV-1, the causative agent of AIDS, mainly infect...

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Detalles Bibliográficos
Autores principales: Aso, Hirofumi, Ito, Jumpei, Koyanagi, Yoshio, Sato, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423081/
https://www.ncbi.nlm.nih.gov/pubmed/30915053
http://dx.doi.org/10.3389/fmicb.2019.00429