Covalent Modification by Glyoxals Converts Cytochrome c Into its Apoptotically Competent State

The effects of glycation by glyoxal (Gly) and methylglyoxal (MGly) on the early and late conformational alterations in Cytochrome c (Cyt c) were studied. Spectroscopic measurements revealed that Cyt c undergo certain conformational alterations and exposure of heme upon overnight incubation with Gly...

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Detalles Bibliográficos
Autores principales: Sharma, Gurumayum Suraj, Warepam, Marina, Bhattacharya, Reshmee, Singh, Laishram Rajendrakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423144/
https://www.ncbi.nlm.nih.gov/pubmed/30886207
http://dx.doi.org/10.1038/s41598-019-41282-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423144/
https://www.ncbi.nlm.nih.gov/pubmed/30886207
http://dx.doi.org/10.1038/s41598-019-41282-2

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