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Covalent Modification by Glyoxals Converts Cytochrome c Into its Apoptotically Competent State
The effects of glycation by glyoxal (Gly) and methylglyoxal (MGly) on the early and late conformational alterations in Cytochrome c (Cyt c) were studied. Spectroscopic measurements revealed that Cyt c undergo certain conformational alterations and exposure of heme upon overnight incubation with Gly...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423144/ https://www.ncbi.nlm.nih.gov/pubmed/30886207 http://dx.doi.org/10.1038/s41598-019-41282-2 |