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The deubiquitinating enzyme USP25 binds tankyrase and regulates trafficking of the facilitative glucose transporter GLUT4 in adipocytes

Key to whole body glucose homeostasis is the ability of fat and muscle cells to sequester the facilitative glucose transporter GLUT4 in an intracellular compartment from where it can be mobilized in response to insulin. We have previously demonstrated that this process requires ubiquitination of GLU...

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Detalles Bibliográficos
Autores principales: Sadler, Jessica B. A., Lamb, Christopher A., Welburn, Cassie R., Adamson, Iain S., Kioumourtzoglou, Dimitrios, Chi, Nai-Wen, Gould, Gwyn W., Bryant, Nia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423145/
https://www.ncbi.nlm.nih.gov/pubmed/30886164
http://dx.doi.org/10.1038/s41598-019-40596-5