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Ketone Bodies Inhibit the Opening of Acid-Sensing Ion Channels (ASICs) in Rat Hippocampal Excitatory Neurons in vitro

Objectives: Despite the long-term efficacy of antiepileptic drug treatments, frequent attacks of drug-resistant epilepsy necessitate the development of new antiepileptic drug therapy targets. The ketogenic diet is a high-fat, low-carbohydrate diet that has been shown to be effective in treating drug...

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Detalles Bibliográficos
Autores principales: Zhu, Fei, Shan, Wei, Xu, Qinlan, Guo, Anchen, Wu, Jianping, Wang, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423181/
https://www.ncbi.nlm.nih.gov/pubmed/30915014
http://dx.doi.org/10.3389/fneur.2019.00155