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DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
Failure of the heat shock response is a key event that leads to insulin resistance and type 2 diabetes. We recently showed that DNAJB3 co-chaperone is downregulated in obese and diabetic patients and that physical exercise restores its normal expression with a significant improvement of the clinical...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423224/ https://www.ncbi.nlm.nih.gov/pubmed/30886231 http://dx.doi.org/10.1038/s41598-019-41244-8 |