Novel Peptide Inhibitors for Lactate Dehydrogenase A (LDHA): A Survey to Inhibit LDHA Activity via Disruption of Protein-Protein Interaction

Lactate dehydrogenase A (LDHA) is a critical metabolic enzyme belonging to a family of 2-hydroxy acid oxidoreductases that plays a key role in anaerobic metabolism in the cells. In hypoxia condition, the overexpression of LDHA shifts the metabolic pathway of ATP synthesis from oxidative phosphorylat...

Descripción completa

Detalles Bibliográficos
Autores principales: Jafary, Farzaneh, Ganjalikhany, Mohamad Reza, Moradi, Ali, Hemati, Mahdie, Jafari, Sepideh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423238/
https://www.ncbi.nlm.nih.gov/pubmed/30886157
http://dx.doi.org/10.1038/s41598-019-38854-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423238/
https://www.ncbi.nlm.nih.gov/pubmed/30886157
http://dx.doi.org/10.1038/s41598-019-38854-7

Ejemplares similares